Musculoskeletal Regenerative Engineering: Biomaterials, Structures, and Small Molecules
Figure 3
(a) A chitosan microsphere formed by ionotropic gelation; (b) cross-sectional view of a chitosan microsphere; (c) a 3D chitosan scaffold fabricated by solvent/heat sintering microspheres; (d)–(f) MC3T3-E1 osteoblast-like cell proliferation on the 3D chitosan scaffold at days 4, 7, and 14, respectively. Cells initially attached and proliferated on the microsphere surfaces and migrated to the neighboring microspheres.
