Musculoskeletal Regenerative Engineering: Biomaterials, Structures, and Small Molecules
Figure 5
Effect of solvent/nonsolvent composition on the morphology of the resulting sintered microsphere scaffolds. Acetone is a solvent for CA while cyclohexane is a nonsolvent. Acetone : cyclohexane ratio was varied 1 : 0, 2 : 1, 3 : 1, 4 : 1, and 5 : 1. The 30x and 100x SEM images of CA scaffolds with varying acetone/cyclohexane sintering solution concentrations: (a) 2 : 1 30x, (b) 2 : 1 100x (c) 3 : 1 30x, (d) 3 : 1 100x, (e) 4 : 1 30x, (f) 4 : 1 100x, (g) 5 : 1 30x, and (h) 5 : 1 100x. Higher solvent compositions led to greater bonding between adjacent microspheres. “Republished with permission of American Scientific Publishers (ASP), from Cellulose and collagen derived micronanostructured scaffolds for bone tissue engineering, Aravamudhan et al., 9 [4], 2013; permission conveyed through Copyright Clearance Center, Inc.”
