Musculoskeletal Regenerative Engineering: Biomaterials, Structures, and Small Molecules
Figure 6
SEM micrographs ((b) and (c)) illustrate the top view of CA-micronanostructured scaffold surface morphology where A is a control CA microstructured scaffold. Micrographs (a)–(d) were recorded on an environmental SEM without applying Au-Pd coating. Representative micrographs (d)–(f) illustrate the deep interior surface morphology of the composite scaffolds taken on several randomly broken pieces of the different scaffolds. Micrographs (e) and (f) at higher magnifications were imaged after coating with Au-Pd using a FESEM. Preferred Collagen nanofiber ( nm) assembly on the microsphere surface may be attributed to polysaccharide hydrophilic nature as well as slower water evaporation during scaffold drying process. Collagen coating was uniform throughout the scaffold 3D architecture with enhanced surface area as compared to neat CA scaffolds. “Republished with permission of American Scientific Publishers (ASP), from Cellulose and collagen derived micronanostructured scaffolds for bone tissue engineering, Aravamudhan et al., 9 [4], 2013; permission conveyed through Copyright Clearance Center, Inc.”
