Musculoskeletal Regenerative Engineering: Biomaterials, Structures, and Small Molecules
Figure 7
(a) 6-Bnz-cAMP increases ALP activity. ALP activities of MC3T3-E1 cells were induced by 6-Bnz-cAMP at day 7 and further increased at day 14. (b) Osteoblast-like MC3T3-E1 cells cultured in mineralization medium supplemented with 6-Bnz-cAMP further enhanced calcium deposition when compared to cells cultured in the mineralization medium alone at day 21. “The small molecule PKA-specific cyclic AMP analogue as an inducer of osteoblast-like cells differentiation and mineralization/Kevin W.-H. Lo et al./Journal of Tissue Engineering and Regenerative Medicine and 6/1. Copyright (c) 2011 John Wiley & Sons, Ltd.”
