The Biological Side of Water-Soluble Arene Ruthenium Assemblies
Figure 19
Fluorescence recorded by flow cytometry of the metalla-prism [Ru6(-cymene)6(tpt)2(dhnq)3]6+ (A) and of 1-(4,6-dichloro-1,3,5-triazin-2-yl)pyrene encapsulated in the metalla-prisms [Ru6(-cymene)6(tpt)2(dhnq)3]6+ (B), [Ru6(-cymene)6(tpt)2(doaq)3]6+ (C), and [Ru6(-cymene)6(tpt)2(dotq)3]6+ (D), indicating pyrene-R released from the host (blue bars). Ruthenium uptake determined by ICP-MS is also shown (red bars). A2780 cells were incubated with the metalla-prism [Ru6(-cymene)6(tpt)2(dhnq)3]6+ and with pyrene-R encapsulated in the three metalla-prisms at 2 μm concentration for 24 h, adapted from [82].
