Synthesis and Antimicrobial Activity of Some Novel Heterocyclic Candidates via Michael Addition Involving 4-(4-Acetamidophenyl)-4-oxobut-2-enoic Acid

Table 1

Sample	Inhibition zone diameter (mm/mg sample)
	Escherichia coliATCC 25922; (G−)	Pseudomonas aeruginosa ATCC 27853; (G−)	Staphylococcus aureus ATCC 25922; (G+)	Bacillus subtilis MTCC 121; (G+)
2b	++	+	+	++
2e	+	+	+	−
3	+	−	+	+
6	++	++	+	+
8	+	+	+	−
10	+++	+	+++	++
11	++	++	++	−
15	+++	−	+++	++

−: no activity, +: weak activity (diameter 5 : 10 mm), ++: moderate activity (diameter 10 : 15 mm), and +++: strong activity (diameter > 15 mm).