Cu(II) Complexes of Isoniazid Schiff Bases: DNA/BSA Binding and Cytotoxicity Studies on A549 Cell Line

Table 2

DNA binding constants (𝐾_𝑏), Stern-Volmer quenching constants, 𝜆_max, and % hypochromism for the interaction of ligands L1–L4 and complexes C5–C8 with DNA.

Compound	𝐾𝑏 (M^−1)	𝜆max (nm)	% hypochromism
L1	5.7×10^4	299	11
L2	4.3×10^4	288	10
L3	1.7×10^4	326	9
L4	2.0×10^4	316	15
C5	1.8×10^4	325	48
C6	3.4×10^4	293	24
C7	1.4×10^4	332	28
C8	4.2×10^4	274	27