A Conformational Model for MTPA Esters of Chiral N-(2-Hydroxyalkyl)acrylamides

Table 1

Conformers of both diastereomers of 3b.

Compound	Diastereomer	Tor1 (°)	Tor2 (°)	(Kcal/mol)	%P
(R)-3b	(2R,2′R)	178	1	1.54	4.2
		−66	2	0.54	22.6
		−70	5	0.00	56.5
		66	2	0.72	16.7
(S)-3b	(2R,2′S)	73	−5	0.59	17.4
		−49	−4	1.70	2.6
		69	1	0.34	26.6
		−76	4	1.88	2.0
		−177	7	0.00	47.3
		168	4	1.60	3.1
		165	0	2.44	0.8
		162	−2	3.02	0.3
		−54	1	1.64	2.9
		156	−108	2.99	0.3
		−62	−140	1.72	2.6