Metal-Enhanced Fluorescence and FRET in Multilayer Core-Shell Nanoparticles

Figure 17

DNA detection using polymer-induced particle networks: (a) target-ready NP aggregate following partial charge neutralization by cationic polymer; (b) hybridization of target oligonucleotides activates polymer transducer as RET donor toward dye-doped silica shell; excitation at 410 nm generates fluorescence by acceptor molecules at 550 nm. (Reprinted with permission from [19], Copyright 2011 American Chemical Society).