Metal-Enhanced Fluorescence and FRET in Multilayer Core-Shell Nanoparticles
Figure 18
(a) Calibration curves for 20 mer single-stranded DNA targets measured with target-ready NPs: perfectly matched (squares) and two-mismatch (diamonds) targets. The open circle indicates the signal recorded for a 100x excess of the two-mismatch sequence. Limit of detection for perfectly matched targets is molecules or 20 zmol in a volume of 20 μL. (b) Example of fluorescence image recorded by IFC. (Reprinted with permission from [19], Copyright 2011 American Chemical Society; [43], Copyright 2013 The Royal Society of Chemistry).