In Silico Molecular Docking Analysis of Natural Pyridoacridines as Anticancer Agents

Table 3

Different glide parameters of known inhibitors.

S. Number	Known inhibitors (cancer macromolecule)	Glide GScore	Glide energy	Glide Van der Waals energy	Glide coulomb energy
1	SU9516 (CDK-2)	−8.997	−37.781	−32.025	−5.756
2	Pyridostatin pentahydrochloride (G-Quadruplex)	−8.846	−81.019	−71.821	−9.199
3	Palbociclib (CDK-6)	−8.066	−53.366	−49.816	−3.55
4	OSI-906 (IGF-1R kinase)	−6.518	−43.453	−39.081	−4.372
5	HA14-1 (Bcl-2)	−4.837	−29.911	−26.702	−3.209
6	AG879 (VEGFR-2)	−1.832	−18.501	−12.745	−5.756