Research Article
Identification and Structural Characterization of Unidentified Impurity in Bisoprolol Film-Coated Tablets
Figure 1
Typical HPLC chromatograms of (a) bisoprolol fumarate working standard and (b) film-coated tablets according to Ph.Eur monograph for bisoprolol fumarate drug substance (Supplement 6.1 04/2008: 1710).
(a) HPLC chromatogram of bisoprolol fumarate working standard |
(b) HPLC chromatogram of drug product during the shelf-life stability program |