Congenital Hypothyroidism: An Audit and Study of Different Cord Blood Screening TSH Values in a Tertiary Medical Centre in Malaysia
Table 3
Clinical profile of term babies with confirmed CH on follow-up.
Number
Sex
Ethnicity
Cord blood TSH (mIU/L)
Venous blood at days 3–5
Current age (years)
Thyroid scan (performed at 3 years of age)
TFT results after 4 weeks’ cessation of L-thyroxine at 3 years of age
Comment
TSH (mIU/L)
FT4 (pmol/L)
TSH
FT4
1
F
M
26.44
25.17
16.5
4
Normal
20.42
10.5
2
F
M
101.09
39
14.9
5
Absent glands
193.7
7.2
3
M
C
28.64
14.37
20.7
5
Normal
26.69
13.3
4
M
M
167.4
259.5
8.4
3.5
Normal
7.4
23
5
M
C
28.73
22.67
21
4
Normal
43.58
29.9
6
F
M
362.2
150
13
3.5
Sublingual thyroid
521
4.5
7
F
M
25.45
26.39
27.6
2
NA
NA
L-thyroxine stopped at 13 months of age
8
M
M
28
19.3
20
3
NA
NA
Down syndrome
9
F
C
30.69
34.78
15.3
2
NA
NA
10
F
M
30.49
14.86
24
2
NA
NA
11
F
M
360
377
9.3
1.5
NA
NA
12
F
C
75.76
69.7
NA
1.5
NA
NA
Mild speech delay, widened AF
13
M
M
70.59
139.7
16.7
0.75
NA
NA
14
F
I
96.73
58.1
16.8
5
—
—
Defaulted follow-up
Sex: M: male and F: female. Ethnicity: M: Malay and C: Chinese. None of the patients were noted to have developmental delay except for patient number 12. All were still on L-thyroxine except for patient number 7.
