Table of Contents
Advances in Endocrinology
Volume 2016, Article ID 9753154, 8 pages
Research Article

Predictors of Erectile Dysfunction in Men with Type 2 Diabetes Mellitus Referred to a Tertiary Healthcare Centre

1Department of Internal Medicine, College of Medicine, Enugu State University of Science and Technology, PMB 01660, Enugu, Nigeria
2Department of Internal Medicine, Federal Medical Centre, Umuahia, Nigeria
3Department of Internal Medicine, University of Uyo Teaching Hospital, Uyo, Nigeria
4Department of Internal Medicine, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria

Received 26 August 2015; Revised 30 January 2016; Accepted 18 February 2016

Academic Editor: Massimiliano Ruscica

Copyright © 2016 Theophilus Ugwu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. The frequency of erectile dysfunction (ED) complicating diabetes mellitus (DM) is reportedly high. However, its risk factors have not been well studied. Methods. This was a cross-sectional study of 160 male type 2 DM adults, aged 30–70 years, attending a tertiary healthcare clinic. Demographic and relevant clinical information was documented. Erectile function was assessed using an abridged version of the International Index of Erectile Function (IIEF-5). All subjects were evaluated for central obesity, glycemic control, peripheral arterial disease (PAD), autonomic neuropathy, dyslipidemia, and testosterone deficiency. Results. 152 (95%) patients with a mean age of 60.3 ± 8.8 years completed the study. 71.1% had varying degrees of ED, while 58.3% suffered from a moderate-to-severe form. Independent predictors of ED [presented as adjusted odds ratio (95% confidence interval)] were longer duration of DM, 1.14 (1.02–1.28), PAD, 3.87 (1.28–11.67), autonomic neuropathy, 3.51 (1.82–6.79), poor glycemic control, 7.12 (2.49–20.37), and testosterone deficiency, 6.63 (2.61–16.83). Conclusion. The prevalence of ED and its severe forms was high in this patient population. Poor glycemic control and testosterone deficiency were the strongest risk factors for ED, making it possibly a preventable condition.