Evaluation of Prepubertal Patients with Suspected Neurosecretory Dysfunction of Growth Hormone Secretion: Diagnostic Steps and Treatment Response

Table 4

Correlations of night profile parameters with first-year’s response data of the NSD patients (Spearman’s method). indicates a level of significance: <0,05; indicates a level of significance: <0,01.

			H-SDS 1 year	HV 1 year	HV-SDS 1 year	Delta H-SDS	Delta HV	Delta HV-SDS	IGF-I-SDS at 3 months	IGFBP3-SDS at 3 months
Spearman-Rho	Number of peaks		,147	,156	,236	,057	,030	,136	−,032	−,168
		Significance	,359	,330	,138	,723	,851	,401	,834	,294
	Maximal secretion		−,061	−,075	,220	,046	−,004	,059	,036	−,141
		Significance	,704	,643	,168	,775	,978	,718	,813	,379
	Mean secretion		,099	,066	,33	,109	,096	,267	−,082	−,071
		Significance	,534	,677	,032	,492	,545	,092	,582	,653