Ribavirin at the Era of Novel Direct Antiviral Agents for the Treatment of Hepatitis C Virus Infection: Relevance of Pharmacological Monitoring

Table 2

Patient characteristics and initial ribavirin dosage.

Patients	Dialysis patients; () (%)	Patients with moderate or severe renal insufficiency; () (%)
HCV genotype
1	10 (58.8)	36 (78.3)
2	2 (11.8)	4 (8.7)
3	2 (11.8)	5 (10.5)
4	3 (17.6)	1 (2.3)
Fibrosis
F0/F1/F2	12 (70.6)	29 (63.0)
F3/F4	5 (29.4)	17 (47.0)
Mean haemoglobin level (g/dL) [IQR]	11.9 [9.9–13.7]	12.7 [11.0–15.1]
Mean ribavirin dosage at D0 (mg/day)	165	560
Mean dosage/weight (mg/kg/day)	2.7	10.4