Review Article

Hepatitis B Virus Infection and the Kidney: Renal Abnormalities in HBV Patients, Antiviral Drugs Handling, and Specific Follow-Up

Table 2

Drug dosing recommendations for adefovir in CHB patients with CKD.

eGFR (mL/Min)Dosage recommended

≥9010 mg/day
<90–5010 mg/day
<50–2010 mg every 48 hours
<20–1010 mg every 72 hours
<1010 mg once a week
HD*10 mg once a week
CAPDND

*In hemodialysis patients, adefovir should be administered on a hemodialysis day, after the session.
eGFR: estimated glomerular filtration rate; ND: no data.
Source: http://www.sitegpr.com/.