Calcium Carbonate versus Sevelamer Hydrochloride as Phosphate Binders after Long-Term Disease Progression in 5/6 Nephrectomized Rats

Figure 1

The flow chart of the study. Surgery (5/6 nephrectomy, NX; Sham-operation, Sham) was performed at entry, followed by 15-week disease progression period. The animals were then allocated to control (0.3% calcium; Sham, NX), 3% calcium carbonate (Ca-Sham and Ca-NX), or 3% sevelamer-HCl diet (Seve-Sham and Seve-NX) for 9 weeks. The values in parentheses indicate the number of animals/group at each phase of the experiment.