Based on Network Pharmacology-Quercetin, a Component of Fuzheng Yiliu Decoction Suppressed Prostate Cancer by Regulating PI3K/AKT Pathway

Figure 1

Network pharmacological analysis of Fuzheng Yiliu decoction (FZYLD). (a) Venn diagram showed the potential targets of FZYLD and prostate cancer (PCa). (b) Protein-protein interaction (PPI) network of 198 potential targets. The targets are represented as nodes in the plot, and their interactions are denoted by lines. The size and color of the nodes represent degree values and change patterns, respectively. The gene of darker color and greater circle shows the higher degree values in this network, whereas the lighter color and the smaller circle show smaller degree values. The thickness of the line, from thick to thin, indicates the edge betweenness from large to small. (c) Topological analysis shows the top 20 target proteins. (d) FZYLD-PCa-target network diagram. The lavender diamond represents the active compound, the green circle represents the target of the drug acting on the disease, the blue hexagon represents the herbal medicine, and the orange rectangle represents the disease (PCa).

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