Clinical Pregnancy Is Not Associated with Sperm Quality in POSEIDON Group 1 and 2 Patients
Table 2
IVF outcomes of studied participants according to semen analysis.
Parameters
Normozoospermia ()
Teratozoospermia ()
OAT ()
Astenoteratozoospermia ()
Severe OAT ()
Cryptozoospermia ()
value
Number of retrieved oocytes
5 (4, 7)
6 (5, 7)
6 (5, 7)
6 (5, 7)
7 (5, 8)
6 (5, 8)
NS
Number of matured oocytes following injection
5 (3, 6)c
5 (4, 6)e
5 (4, 6)e
5 (4, 6)e
5 (4, 7)f
5 (3, 6)
0.042
Number of fertilized oocytes
3 (2, 4)
4 (3, 5)c,f
3 (2, 4)
3 (2, 5)f
3 (2, 5)
3 (2, 4)
0.003
ICSI method
3 (2, 5)
4 (3, 5)
4 (2, 4)
3 (2, 4)
3 (2, 5)
—
NS
IMSI method
4 (2, 4)
4 (3, 5)
3 (2, 5)
4 (3, 5)
4 (2, 5)
—
Abnormal fertilization (1PN, 3PN, etc.) ( (%))
3 (9.1%)
44 (12.9%)
27 (13.2%)
66 (12.7%)
9 (10%)
15 (19.7%)
NS
Number of cleavage embryos
3 (2, 4)
4 (3, 5)c
3 (2, 4)
3 (2, 5)f
4 (2, 5)f
3 (2, 4)
0.001
Number of good cleavage quality
1 (1, 3)
2 (1, 3)
2 (1, 2)
2 (1, 3)
1.5 (1, 2)
1 (1, 2)
NS
Number of blastocyst embryos
2 (1, 4)f
2 (1, 4)d,f
2 (0, 4)
2 (0, 4)f
2 (0, 4)f
1 (0, 3)
0.003
Number of good blastocyst quality
1 (0, 2)d,e,f
0 (0, 1)d,f
0 (0, 1)
0 (0, 1)
0 (0, 1)
0 (0, 1)
0.036
Number of embryo transfer
1 (1, 2)
2 (1, 2)
2 (1, 2)
2 (1, 2)
2 (1, 2)
2 (1, 2)
NS
Embryo transfer day
D2/3 embryo transfer ( (%))
14 (42.4%)
217 (63.8%)
136 (66.7%)
360 (69.2%)a
60 (66.7%)
58 (76.3%)a
0.003
D5/6 embryo transfer ( (%))
19 (57.6%)d,f
123 (36.2%)
68 (33.3%)
160 (30.8%)
30 (33.3%)
18 (23.7%)
Overall clinical pregnancy ( (%))
13 (39.4%)
126 (37.1%)
82 (40.2%)
181 (34.8%)
32 (35.6%)
34 (44.7%)
NS
ICSI method ( (%))
5 (26.3%)
62 (35.4%)
36 (37.5%)
110 (37.3%)
19 (35.8%)
—
NS
IMSI method ( (%))
8 (57.1%)
64 (38.8%)
46 (42.6%)
71 (31.6%)
13 (35.1%)
—
D2/3 clinical pregnancy ( (%))
6 (46.2%)
82 (65.1%)
51 (62.2%)
126 (69.6%)
22 (68.8%)
22 (64.7%)
NS
D5/6 clinical pregnancy ( (%))
7 (53.8%)
44 (34.9%)
31 (37.8%)
55 (30.4%)
10 (31.3%)
12 (35.3%)
NS
Note: data are presented as median (Q1 and Q3), and the Kruskal-Wallis test is used. Data are presented as the number of subjects and percentage ( (%)), and chi-square tests are used for the categorical variable. aCompared by normozoospermia. bCompared by teratozoospermia. cCompared by OAT. dCompared by astenoteratozoospermia. eCompared by severe OAT. fCompared by cryptozoospermia.
