Effect of Cycas pectinata Seed Extract on Testicular Steroidogenesis in a Mouse Model

Table 2

Binding affinity and the residues involved in the interaction of phytochemical compounds with CYP11A1.

Compounds	Binding affininity (kcal/mol)	Residues involved in H-bond	Residues involved in other interactions (π-alkyl and alkyl)
Hupehemonoside	-10.7	Asn210, Gln377, Val353	Leu460, Ile84, Leu101
Pyrrhoxanthinol	-10.4	Arg81	Ile84, Val101, Leu209, Val353, Phe548, Leu460, Ile461, Lue355
Pseudojervine	-10.3	Asn210, Arg81	Leu209, Phe82, Phe548, Val353, Leu460
Cyclogaleginoside A	-10.3	Phe82	Leu209, Phe548, Val353, Leu460, Trp87, Ile84, Phe82
Cyclopyrroxanthin	-10.0	Glu283	Leu101, Leu424, Leu209, Phe548, Val353, Val35, His29, Ile84, Phe82, cys423
Pyrrhoxathinol 5,8-furanoide	-9.6		Arg81, Phe82, Leu101, Leu424, Leu209, Phe548, Met284, His39, Val100, Val35, cys423, Val353, Val57, Ile84
3-Didehydro-5-dehydroxyhydratoperidinin	-9.1		Leu101, Leu424, Met284, Cys423, Ile84, Leu209, Val353