Curcumin Attenuates Ferroptosis and Ameliorates Erectile Function in Diabetic Rats by Activating Nrf2/HO-1 Pathway

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Gene</td><td class="align_center">Forward primer</td><td class="align_center">Reverse primer</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Slc7a11</td><td class="align_center">5′-TGAATGCCTTGTCTGCTTTG-3′</td><td class="align_center">5′-GAATTGCAGGGAACTGTGGT-3′</td></tr><tr><td class="align_left">GPX4</td><td class="align_center">5′-TCAGCAAGATCTGCGTGAAC-3′</td><td class="align_center">5′-GGGGCAGGTCCTTCTCTATC-3′</td></tr><tr><td class="align_left">Nrf2</td><td class="align_center">5′-TGCCCACATTCCCAAACAAG-3′</td><td class="align_center">5′-GCTATCGAGTGACTGAGCCT-3′</td></tr><tr><td class="align_left">HO-1</td><td class="align_center">5′-CGCCTCCAGAGTTTCCGCCTCCAAC-3′</td><td class="align_center">5′-ATAGACTGGGTTCTGCTTGTTTCGC-3′</td></tr><tr><td class="align_left">GAPDH</td><td class="align_center">5′-AACGGATTTGGTCGTATTGGG-3′</td><td class="align_center">5′-CCTGGAAGATGGTGATGGGAT-3′</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>Note: Slc7a11 = solute carrier family 7 member 11; GPX4 = glutathione peroxidase 4; Nrf2 = nuclear factor erythroid 2-related factor 2; HO-1 = heme oxygenase-1. </div></td></tr></table>

<div>Primers sequences for determination of mRNA expression levels.</div>

Andrologia

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Table 1

Table 1: Curcumin Attenuates Ferroptosis and Ameliorates Erectile Function in Diabetic Rats by Activating Nrf2/HO-1 Pathway 