Structure-Function Relationships behind the Phenomenon of Cognitive Resilience in Neurology: Insights for Neuroscience and Medicine
Examples of resilience to brain damage. (a) A 44-year-old civil servant and father of two with relatively low intelligence, but normal social functioning, was found to have preserved mental abilities despite significant ventricular enlargement and a very thin cortical mantle due to a history of hydrocephaly . (b) Roger: patient with bilateral destruction of the limbic system following herpes simplex virus encephalitis. Contrary to all expectations, the patient presents largely preserved cognition and self-awareness (adapted from ).