Advances in Neuroscience / 2015 / Article / Tab 1

Review Article

Contemporary Review of the Management of Brain Metastasis with Radiation

Table 1

Dose fractionation schemes of WBRT in various tumor types.

Study Number of patients Randomization Gy/# fractionsMedian survival (months)

Harwood and Simpson [18]101 30/10 versus 10/14.0–4.3
Kurtz et al. [19] 255 30/10 versus 50/203.9–4.2
Borgelt et al. [17, 20]138 10/1 versus 30/10 versus 40/204.2–4.8
Borgelt et al. [17, 20]64 12/2 versus 20/52.8–3.0
Chatani et al. [21]70 30/10 versus 50/203.0–4.0
Haie-Meder et al. [22] 216 18/3 versus 36/6 or 43/134.2–5.3
Chatani et al. [23]72 30/10 versus 50/20 or 20/52.4–4.3
Murray et al. [24] 445 54.4/34 versus 30/104.5

Adapted from Khuntia et al. [25].

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