Advances in Neuroscience / 2015 / Article / Tab 3

Review Article

Contemporary Review of the Management of Brain Metastasis with Radiation

Table 3

RTOG 9005 [29].

Tumor diameter ≤20 mm21–30 mm31–40 mm
DoseToxicityDoseToxicityDoseToxicity

18 Gy8%15 Gy13%12 Gy10%
21 Gy11%18 Gy20%15 Gy14%
24Gy10%21 Gy38%18 Gy50%
24 Gy58%

The MTD for tumors ≤20 mm is 24 Gy, for tumors 21–30 mm it is 18 Gy, and for tumors 31–40 mm it is 15 Gy. Doses in yellow represent the recommended MTD.

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