Table of Contents
Advances in Orthopedic Surgery
Volume 2016, Article ID 1979348, 6 pages
Clinical Study

Early Clinical Outcomes Associated with a Novel Osteochondral Allograft Transplantation System in the Knee

1Insall Scott Kelly Institute, New York, NY 10065, USA
2New York University, New York, NY 10065, USA
3Hospital for Joint Disease, NYU, New York, NY 10065, USA
4St. Francis Hospital, Roslyn, NY 11548, USA
5Norton Healthcare, Louisville, KY 40207, USA
6Department of Orthopaedic Surgery, University of Louisville, Louisville, KY 40202, USA
7Southside Hospital, Bay Shore, NY 11706, USA
8Lenox Hill Hospital, Northwell Health System, New York, NY 10065, USA

Received 8 November 2015; Revised 7 March 2016; Accepted 10 March 2016

Academic Editor: Werner Kolb

Copyright © 2016 William J. Long et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Osteochondral defects of the knee are a common finding at the time of arthroscopic intervention. Purpose/Hypothesis. To report our outcomes after utilizing a new technique of osteochondral allograft transplantation for focal cartilage defects. Study Design. Case series. Methods. All patients treated with osteochondral allograft transplantation with a Zimmer Chondrofix plug (Zimmer Inc., Warsaw, IN) for focal cartilage defects over a 12-month period were followed up at a minimum of 24 months. Failures were documented and radiographs were evaluated. Results. 61 knees (58 patients) underwent grafting. Three cases were lost to follow-up. In the remaining 58 cases the average age was 40 (range 18–59). At a mean follow-up of 28 months (range 24–36), there were 5 failures requiring further surgery. Mean KOOS scores in the Pain, Symptoms, ADL, Sports, and Quality of Life dimensions were 82, 79, 84, 66, and 58, respectively. Radiographs demonstrated maintenance of the subchondral bone without graft absorption or subsidence. Conclusions. Our observations suggest that osteochondral allograft transplantation leads to a satisfactory activity level and function at early follow-up while avoiding the inherent complexities associated with other cartilage restoration techniques. Longer follow-up is warranted to monitor the subchondral bone, articular surface, and patient outcome measures.