Research Article

A New 3D Simulation Method for the Construction of Optical Phase Contrast Images of Gold Nanoparticle Clusters in Biological Cells

Figure 2

(a) Schematic representation of an OPCM. (b) 2D visual representation of the FDTD OPCM model using incoherent illumination by two planes waves at a polar angle of 30 degrees. For each of the two plane waves, the propagation of light is modeled as a combination of two parallel wave phenomena: (i) propagation of the reference (R) beam without the cell, and (ii) propagation of the diffracted (D) beam due to the cell.
727418.fig.002a
(a)
727418.fig.002b
(b)