Prophylactic Effects of Ethanolic Extract of Irvingia gabonensis Stem Bark against Cadmium-Induced Toxicity in Albino Rats
Table 4
Changes in the levels of hepatic and cardiac antioxidant parameters in cadmium-induced rats treated with ethanolic extract of Irvingia gabonensis.
Treatment
Liver
Heart
GSH
GPx
SOD
CAT
GSH
GPx
SOD
CAT
(mg/g tissue)
(U/mg protein)
(mg/g tissue)
(U/mg protein)
Control
25.85 ± 0.15
35.55 ± 0.83
37.36 ± 1.01
35.57 ± 1.08
36.06 ± 1.11
45.74 ± 5.74
57.03 ± 0.01
9.37 ± 0.81
Cadmium untreated
10.23 ± 0.21*
14.65 ± 0.41*
18.23 ± 0.68*
20.22 ± 0.58*
29.21 ± 1.41*
25.26 ± 1.10*
43.26 ± 0.71*
5.57 ± 0.31*
Cadmium + 200 mg/kg
23.33 ± 0.24**
34.23 ± 0.45**
35.88 ± 0.03**
32.89 ± 0.41**
34.65 ± 2.14**
37.02 ± 1.44**
54.16 ± 0.37**
7.22 ± 0.36**
Cadmium + 400 mg/kg
24.21 ± 0.27**
34.48 ± 0.21**
36.34 ± 1.00**
34.12 ± 0.81**
35.23 ± 1.32**
38.18 ± 1.22**
56.15 ± 0.21**
8.98 ± 0.47**
Values are means ± s.e.m. of 5 animals per group; cadmium treated = Irvingia gabonensis at 200 mg/kg; cadmium treated = Irvingia gabonensis at 400 mg/kg; *significantly different from control (); **significantly different from cadmium untreated ().
