A Comprehensive Review on Dry Eye Disease: Diagnosis, Medical Management, Recent Developments, and Future Challenges

Table 3

Few marketed preparations for treatment of keratoconjunctivitis sicca.

Manufacturer	Brand	Content	Delivery system and indication
Allergan, Inc.	Restasis (by prescription)	Cyclosporin A 0.05% w/v	Oil-based emulsion; DED treatment
	Refresh Optive	Contains 2 osmolytes L-carnitine and erythritol and CMC sodium 5 mg	Eye drops
Sun Pharma Ind. Ltd.	Cyclomune	Cyclosporin A 0.05% w/v	Drops; DED treatment
Bausch & Lomb Inc.	Lotemax	Loteprednol etabonate 0.5%	Suspension drops (steroid) for short-term therapy
Novartis Ltd.	Voltaren	Diclofenac sodium ophthalmic solution) 0.1%	Drops
FDC Ltd.	ZO-D eye drops	Ofloxacin and dexamethasone	Drops
Allergan India Pvt. Ltd.	Acular LS	Ketorolac tromethamine 0.4%	Drops
	Toba; Toba DM; Toba F	Tobramycin USP; Tobramycin and dexamethasone; Tobramycin and fluorometholone	Drops
Ocusoft, Inc.	Retaine; MGD	Cationic O/W emulsion technology	Hypotonic emulsion provides lubrication
Otsuka Pharmaceuticals	Mucosta ophthalmic suspension UD2%	Rebamipide	Marketed in China, Japan, Indonesia, Malaysia, and Thailand
Advanced Vision Research	Thera tears nutrition	Omega 3 fatty acids	Gel capsules