Early Detection and Treatment of Psychosis: The Bern Child and Adolescent Psychiatric Perspective

Table 3

Conversion rates for COPER and COGDIS in (sub)samples not systematically treated for psychosis-risk.

Study	BS criterion, ( criterion positive), predominant age group, (%) lost-to-last-follow-up of total sample	Conversion rate at month
		12	18	24	36	>36
[93, 95]	COPER, 160 (106), adults, n.a.; COGDIS, 160 (67), adults, n.a.	20%; 24%		37%; 46%	50%; 61%	65%^c; 79%^c
[97]	COPER, 146 (146), adults, 60 (41%)^b; COGDIS, 146 (124), adults, 60 (41%)^b	25%; 25%		33%; 33%
[98]^a	COPER, 128 (64), adults, 23 (36%)^b	17%		20%
[99, 114]	COGDIS, 245 (171), adults, 62 (25%)^b	14%	19%
[101]	COGDIS, 73 (48), adults, n.a.			25%
[102]	COGDIS, 72 (39), adolescents, 15 (21%)^b			18%
[100]	COGDIS, 246 (158), adults, 56 (23%)^b	23%		34%	40%	42%^d

Supportive counselling control condition only; conversion rate includes conversion to a late state, that is, development of APS or BLIPS.
^bThose lost-to-follow-up were conservatively regarded as nonconverters, symptomatic UHR criteria excluded.
^cMinimum of 60 months, maximum of 359 months.
^dMonths 36 to 48.
n.a.: not applicable; only patients with complete follow-up data were included.