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Research Article

Role of Motif III in Catalysis by Acetyl-CoA Synthetase

Table 1

Alignment of motif III residues in Acs sequences.
Consensus YXXGD 
M.  thermoautotrophicus Acs1498YTAGD503
Salmonella enterica Acs496YFSGD501
Saccharomyces cerevisiae Acs1555YFTGD560
Methanosaeta concilii Acs1525YLAGD530
Methanosaeta concilii Acs2545YLAGD550
Methanosaeta concilii Acs3515YLAGD520
Methanosaeta concilii Acs4509YFSGD514
Methanosaeta concilii Acs5514YLAGD519
Homo sapiens ACSM2A442WLLGD446
Alcaligenes sp. AL3007 CBL442WLLGD446
Bacillus cereus DltA379YRTGD383
             *  * 
Positions within each sequence are shown, and conserved residues are indicated with an asterisk. M. thermautotrophicus Acs1, gi:82541817; Salmonella enterica Acs, gi:16767525; Saccharomyces  cerevisiae Acs1, gi:6319264; Methanosaeta concilii Acs1, gi:330506788; Methanosaeta concilii Acs2, gi:330506787; Methanosaeta concilii Acs3, gi:330506786; Methanosaeta concilii Acs4, gi:330506785; Methanosaeta concilii Acs5, gi:330508629; Homo sapiens ACSM2A, gi:58082049; Alcaligenes sp. AL3007 CBL, gi:197725159; Bacillus cereus DltA, gi:226887779.