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Volume 2014, Article ID 671059, 6 pages
Research Article

Genome-Wide miRNA Seeds Prediction in Archaea

1State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China
2Department of Biomedical Engineering, College of Engineering, Peking University, Beijing 100781, China

Received 4 March 2014; Revised 14 April 2014; Accepted 28 April 2014; Published 14 May 2014

Academic Editor: Paola Londei

Copyright © 2014 Shengqin Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary S1: List of candidate seeds that were extracted from 115 archaeal genomes. The conservation signal is above background with a P-value <0.05 followed by Bonferroni post hoc correction.

Supplementary S2: List of miRNA target sites that were detected with ‘Window Conservation Score’ value greater than the ‘Conservation Score of 95th percentile’ in related species. The sites overlapped with coding regions were discarded. See the Material and Methods section for more details.

Supplementary S3: Detail information of the functional enrichment analysis results using DAVID. There are 38 species approved in this analysis. These tables are generated from the DAVID analysis, and we simply integrate them together using the original description. The field definitions are added on the top of each table to make it more clear. The type of GO term or KEGG pathways can be found in the Category column.

  1. Supplementary S1
  2. Supplementary S2
  3. Supplementary S3