Research Article

A Phylogenomic Census of Molecular Functions Identifies Modern Thermophilic Archaea as the Most Ancient Form of Cellular Life

Figure 2

The distribution and evolution of GOTMF terms. (a) A Venn diagram illustrates the sharing patterns of molecular functions in the seven taxonomic groups (reproduced from [28]). Numbers of terms in Venn taxonomic groups and in superkingdoms are given in parentheses and are reflected by the areas of the diagram. (b) A ToF (tree length = 99,594 steps) portraying the evolution of GOTMF terms. Molecular activities present in all three superkingdoms are colored red while those unique to a superkingdom or shared by at most two are colored blue. The inset displays the most basal taxa. GO: 0004715 is the “nonmembrane spanning protein tyrosine kinase activity.”
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