HVO_2299 of Hfx. volcanii clusters with aIF5A. Physical gene clustering links genes encoding agmatinase, DHS, and aIF5A in Euryarchaeota. In pink, aIF5A (HVO_2300 in Hfx. volcanii); in blue, agmatinase (HVO_2299 in Hfx. volcanii); in yellow, gene encoding HVO_2298; DHS (HVO_2297 in Hfx. volcanii). Arrows represent the genes. Physical clustering was analyzed on the STRING database.