Discovering Antioxidant Molecules in the Archaea Domain: Peroxiredoxin Bcp1 from Sulfolobus solfataricus Protects H9c2 Cardiomyoblasts from Oxidative Stress

Figure 1

Alignment of SsBcp1 with the Prx orthologues. The multiple sequence alignment of S. solfataricus Bcp1 (AAK42253), H. sapiens hPrx1 (BAG70076) and hPrx2 (AAH39428), S. cerevisiae Dot5p (DAA08535), and V. vulnificus VvPrx1 (ADV88988) and VvPrx2 (ADV87477) was performed using the MUSCLE algorithm. Identical and similar amino acids are marked with asterisks and points, respectively. The peroxidatic cysteines are indicated in white and the resolving cysteines are underlined; the motifs for the sensitive Prxs are boxed and marked with arrows.