Transfection Studies with Colloidal Systems Containing Highly Purified Bipolar Tetraether Lipids from Sulfolobus acidocaldarius

Figure 9

Visualisation of size and morphology of lipoplexes by atomic force microscopy. (a) 25 kDa bPEI, (b) DOTAP, (c) hGDNT/DOTAP (5 : 95), (d) PLFE/DOTAP (5 : 95), (e) hGDNT/CH/DOTAP (5 : 45 : 50), (f) PLFE/CH/DOTAP (5 : 45 : 50), and (g) hGDNT/PC/CH/DOTAP (5 : 30 : 35 : 30). All formulations were complexed at N/P 2.5–2.7. Inset: 500 × 500 nm.

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