Research Article

Transfection Studies with Colloidal Systems Containing Highly Purified Bipolar Tetraether Lipids from Sulfolobus acidocaldarius

Table 1

Composition and physicochemical properties of polymer and liposomal formulations.

Formulation (mol : mol)Particle size ± SD [nm]AFM diameter [nm]Zeta potential [mV]

25 kDa bPEI
DOTAP84.7 ± 3.465.3+38.5
hGDNT/DOTAP (5 : 95)89.8 ± 6.967.5+40.9
PLFE/DOTAP (5 : 95)94.3 ± 6.970.8+38.1
hGDNT/CH/DOTAP (5 : 45 : 50)96.6 ± 8.863.6+41.1
PLFE/CH/DOTAP (5 : 45 : 50)103.7 ± 49.471.3+45.5
hGDNT/PC/CH/DOTAP (5 : 30 : 35 : 30)96.6 ± 8.867.9+ 48.6