Research Article
Transfection Studies with Colloidal Systems Containing Highly Purified Bipolar Tetraether Lipids from Sulfolobus acidocaldarius
Table 2
Composition and physicochemical properties of polyplexes and lipoplexes.
| Formulation (mol : mol) [N/P ratio] | Particle size ± SD [nm] | AFM diameter [nm] | Zeta potential [mV] |
| 25 kDa bPEI | 60.2 ± 10.2 | 79.5 | +31.2 | DOTAP | | 257.1 | +38.9 | hGDNT/DOTAP (5 : 95) [2.5] | | 317.4 | +41.0 | PLFE/DOTAP (5 : 95) [2.5] | 214.5 ± 10.2 | 210.7 | +42.7 | hGDNT/CH/DOTAP (5 : 45 : 50) | 450.1 ± 4.5 | 473.5 | +50.1 | PLFE/CH/DOTAP (5 : 45 : 50) | 372.3 ± 15.0 | 441.3 | +51.6 | hGDNT/PC/CH/DOTAP (5 : 30 : 35 : 30) | 231.8 ± 35.0 | 398.4 | −48.6 |
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