Review Article

HIV-1 Genetic Variability and Clinical Implications

Figure 2

Different subtype associated RNA templates and development of NRTIs resistance in B and C subtypes. The figure represents the differences between subtype B (a) and subtype C (b), observed at nucleotide level in reverse transcriptase codons 64-65-66. AZT: zidovudine, d4T: stavudine, ddI: didanosine, ABC: abacavir, and TDF: tenofovir (modified by [15]).
481314.fig.002a
(a)
481314.fig.002b
(b)