Pharmacodynamics and Pharmacokinetics Evaluation of Ranitidine Microemulsion on Experimental Animals

Table 3

Thermodynamic stability studies of selected ranitidine microemulsion.

Formulation	Variables	Phase separation		% transmittance		% CDR		Drug precipitation
		After 3 months	After 6 months	After 3 months	After 6 months	After 3 months	After 6 months	After 3 months	After 6 months
R-1	2–8°C	No	No	87.4	87.2			Absent	Absent
	25 ± 2°C	No	No	88.6	88.1			Absent	Absent
	50 ± 2°C	No	No	88.4	88.7			Absent	Absent