Identification and Prevention of Antiepileptic Drug Noncompliance: The Collaborative Use of State-Supplied Pharmaceutical Data

Table 1

Various risk factors for AED noncompliance.

Risk factor	Study	Increased risk	Noncompliance marker
Type of seizures	Al Faris, Santiago, Snodgrass, Loiseau	No	TDM
Illness burden	Santiago, Snodgrass, Loiseau	Yes	TDM
Physician-patient communication	Santiago	Yes	TDM
Total number of pills per day	Santiago, Loiseau	Yes	TDM
Age	Santiago, Buck, Snodgrass, Loiseau	Yes	TDM
Gender	Santiago, Loiseau	No	TDM
Intellectual level	Santiago	Yes	TDM
Compliance with appointment/followup	AlFaris, Snodgrass	Yes	TDM
Perceived stigma	Buck	Yes	TDM
Experience of side effects	Buck	Yes	TDM
Race	Snodgrass	Yes	TDM
Reliance on social security	Snodgrass	Yes	TDM
Insured status	Snodgrass	Yes	TDM
Involvement of caretaker/parent	Snodgrass	Yes	TDM
Type of AED	Al Faris, Lusic	Yes	TDM
Duration of disease	Loiseau	Yes	TDM

Bold: study that found correlation.
Unbold: study that explored relationship but did not find a correlation.
TDM: therapeutic drug monitoring.