Etiopathogenesis of Insulin Autoimmunity

Table 1

Islet autoantigens in type 1 diabetes.

Autoantigen	Autoantibody	Present before clinical onset
Insulin	Insulin autoantibodies	IAA	+
Proinsulin	Proinsulin autoantibodies	PAA	?
Glutamic acid decarboxylase, 65 kD		GAD65A	+
Insulinoma antigen-2		IA-2A	+
ZnT8 transporter		ZnT8A	+