Origin and Regenerative Potential of Vertebrate Mechanoreceptor-Associated Stem Cells

Figure 2

Anterior-posterior gradient of cells Nestin expressing within the rat palate. Cryosections of rat palate were stained with mouse anti-Nestin antibody (clone Rat401) followed by Alexa 555 coupled detection antibody and nuclear counterstaining using Sytox Green. Confocal analysis revealed the presence of numerous Nestin-positive MCs and Merkel cell-neurite complexes within the hard palate (anterior pole), whereas within the soft palate (posterior pole) only few Merkel cell neurites complexes and nearly no MCs were detected.