Autoimmune Thyroid Disease in Rheumatoid Arthritis: A Global Perspective

Table 2

Bivariate analysis of categorical variables.

Characteristic	RA with AITD	RA without AITD	OR	95% CI	P
MAS	10/61 (16.39)	7/650 (1.08)	18.01	6.57–49.30	<0.0001
Type 2 Diabetes	12/72 (16.67)	20/665 (3.01)	6.45	3.00–13.83	0.008
Methotrexate	75/78 (96.15)	627/716 (87.57)	3.54	1.09–11.49	0.024
Female	72/78 (92.31)	575/719 (79.97)	3.01	1.2–7.05	0.008
Thrombosis	9/71 (12.68)	30/667 (4.50)	3.01	1.4–6.78	0.003
Anti La+	6/39 (15.38)	14/246 (5.69)	3.01	1.08–8.3	0.04*
Anti Ro+	11/39 (28.21)	32/248 (12.90)	2.65	1.20–5.84	0.013
Abnormal BMI	37/69 (53.60)	250/612 (40.8)	1.67	1.01–2.76	0.042
Low educational level	15/59 (25.4)	249/633 (39.3)	0.52	0.28–0.96	0.035
Abnormal cholesterol	17/43 (39.53)	162/290 (55.86)	0.51	0.26–0.99	0.045
RF+	50/73 (68.49)	523/644 (81.21)	0.50	0.29–0.85	0.01
Polyautoimmunity	78/78 (100)	35/722 (4.8)	N/A	N/A	N/A
TPOAb+	51/54 (94.44)	0/81 (0.00)	N/A	N/A	N/A
TgAb+	26/50 (52.00)	0/75 (0.00)	N/A	N/A	N/A

∗Fisher’s exact test.
95% CI: 95% confidence interval; AITD: autoimmune thyroid disease; BMI: body mass index; N/A: not assessed; OR: odds ratio; RA: rheumatoid arthritis; RF: rheumatoid factor; TgAb: anti-thyroglobulin; TPOAb: anti-thyroperoxidase enzyme.