Differences in Mammalian Target of Rapamycin Gene Expression in the Peripheral Blood and Articular Cartilages of Osteoarthritic Patients and Disease Activity

Figure 3

Protein concentrations of total p70-S6K (a), phospho-p70-S6K (b), p21 (c), and active caspase 3 (d) measured by ELISA in PBMCs from the “Low mTOR subset” (𝑛=15), the “High mTOR subset” (𝑛=32), and end-stage (𝑛=14) OA patients compared with control subjects (𝑛=27) (set 1). Asterisks indicate significant differences from the healthy control patients (Student’s unpaired 𝑡-test).

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