Progression of Gene Expression Changes following a Mechanical Injury to Articular Cartilage as a Model of Early Stage Osteoarthritis

Figure 1

Fold changes for shear versus axial specimens within each time point. Fold change is shown on the vertical axis as a log scale, and days in culture are shown on the horizontal axis. Error bars for fold changes are depicted and significant differences for the respective comparison are indicated with an asterisk (). A graph is shown for each gene category: cartilage matrix (a), degradative enzymes (b), inflammatory response (c), and apoptosis (d).

(a)

(b)

(c)

(d)