Review Article

Treatment of Nongout Joint Deposition Diseases: An Update

Table 2

Treatment of rare deposits-induced arthropathies.

Specific treatment of the joint involvementEfficacy of colchicineEfficacy of NSAIDsEfficacy of systemic corticosteroidsEfficacy of intra-articular corticosteroid injectionEfficacy of interleukin-1 blocking agentsOther measures improving joint condition

Hereditary hemochromatosisNoNo dataYes (limited data)No dataNo dataYesPhlebotomy (debated)
OxalosisNoNo dataPoorNo dataNo dataPossiblePyridoxine—liver-kidney transplantation (no clear efficacy on arthropathy)
OchronosisNoNo dataYes (limited data)No dataNo dataNo dataLimited protein intake and ascorbic acid—nitisinone (debated)
Wilson's diseaseNoNo data No dataNo dataNo dataNo dataCopper chelators (no clear efficacy on joint involvement)—liver transplantation (one case report)