Evaluation of Antiarthritic Potential of Methanolic Extract of Gentiana kurroo Royle

Table 2

Effect of methanolic extract of Gentiana kurroo on mycobacterium induced adjuvant arthritis in 1st week.

Drug	Dose (mg/kg bw)	Body weight (g); 1st week	Edema (4 days)	Edema (7 days)
Control	NS	145.6 ± 1.29	2.64 ± 0.22	2 ± 0.13
GI	50	148 ± 3.16	2.06 ± 0.12	1.58 ± 0.21
GII	100	149.8 ± 3.14	1.9 ± 0.18^*	1.46 ± 0.17
GIII	250	148.2 ± 3.07	1.68 ± 0.13^*	1.26 ± 0.1^*
GIV	500	150 ± 2.34	1.52 ± 0.17^*	1.12 ± 0.11^*
GV	750	148.2 ± 2.65	1.36 ± 0.15^*	1.02 ± 0.04^*
Diclofenac	20	151 ± 2.76	0.36 ± 0.09^*	0.4 ± 0.06^*

Values are represented as mean ± S.E. (). ^* < 0.05 (control versus treated groups) using one-way ANOVA followed by Tukey’s HSD test.