Research Article
Evaluation of Antiarthritic Potential of Methanolic Extract of Gentiana kurroo Royle
Table 3
Effect of methanolic extract of Gentiana kurroo on mycobacterium induced adjuvant arthritis in 2nd week.
| Drug | Dose (mg/kg bw) | Body weight (g) 2nd week | Edema (11 days)
| Edema (14 days) |
| Control | NS | 156.2 ± 3.64 | 2.14 ± 0.09 | 2.02 ± 0.09 | GI | 50 | 156.4 ± 2.84 | 1.66 ± 0.17 | 1.46 ± 0.27 | GII | 100 | 158.2 ± 3.34 | 1.46 ± 0.28 | 1.28 ± 0.12 | GIII | 250 | 159.2 ± 3.38 | 1.24 ± 0.15* | 1.02 ± 0.21* | GIV | 500 | 158.6 ± 1.94 | 1.08 ± 0.16* | 0.78 ± 0.28* | GV | 750 | 160.2 ± 2.11 | 0.94 ± 0.07* | 0.68 ± 0.09* | Diclofenac | 20 | 159.4 ± 1.69 | 0.64 ± 0.06* | 0.66 ± 0.15* |
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Values are represented as mean ± S.E. (). * < 0.05 (control versus treated groups) using one-way ANOVA followed by Tukey’s HSD test.
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