Arthritis

Arthritis / 2015 / Article / Tab 2

Clinical Study

The Safety and Efficacy of an Enzyme Combination in Managing Knee Osteoarthritis Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial

Table 2

Lequesne Functional Index total scores.

Median score Median 
change
Median 
% change
BaselineWeek 12

Diclofenac13.018.3−4.0*A−32.7*A
(12.0, 13.0)(7.0, 10.0)(−5.5, −2.0)(−42.3, −22.8)

Wobenzym12.09.0−3.3*A−27.4*A
(11.5, 13.0)(8.0, 10.0)(−4.5, −2.0)(−35.7, −16.7)

Placebo12.59.8−2.0*B−16.4*B
(12.0, 12.5)(9.0, 11.5)(−3.5, −0.5)(−28.0, −4.8)

All values presented as median (95% confidence interval).
*Significantly different from “no change” ( < 0.05).
A,BTreatment groups with different superscripts differ within the same column ( < 0.05).

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